You'll find hundreds of files on cleft lip, cleft palate here on widesmiles.org.

This one is about: What is Van Der Woude?


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WHAT IS VAN DER WOUDE?

Van Der Voude Syndrome is a Dominantly inherited condition, present at birth, that includes some or all of the following:

It is an INHERITED condition that is determined at the time of conception. Generally, only a parent with Van Der Woude's Syndrome can produce a child with Van Der Woude's Syndrome, and that recurrence risk is approximately 50%.  The gene that is linked to Van Der Woude Syndrome has been found to be located on the (   ) chromosome. It is a dominant gene, which means that if it is present in the chromosome, it will most likely be manifest in the child.

Each parent provides half of the genetic material for a child. A parent with Van Der Voude Syndrome has a 50/50 chance of sharing the VDW gene with the baby. If that gene is shared, the child is likely to present with Van Der Woude.

Most clefts are NOT dominantly inherited. While a person with VDW has a 50% chance of passing the condition on to her children, a person with an isolated cleft has only approximately a 5% chance of sharing the disorder. For that reason it is imperative that a cleft-affected person seek the assistance of a genetic counselor when deciding their risk of passing the cleft condition to their offspring.


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